Introduction
Microprobes for Life Science Nerve Cuff Electrodes are designed for reliable recording and/or stimulation of peripheral nerves. Our cuffs are suitable for both acute use and chronic implantation, and are available in a large variety of lengths and diameters to best fit the anatomy of your target nerve.
Electrode contact spacing and layout within the cuffs is fully customizable, and arrangement options include clustered, multi-polar, or concentric configurations.
Characteristics
- For both acute and chronic experiments.
- 1 - 24 electrode sites.
- Broad range of available inner diameters, from 5 mm down to as small as 56 µm.
- Concentric configurations, featuring multiple independently-addressable contacts per ring.
- Customizable electrode arrangements, including concentric and extra wide contact options.
- Adaptable to interface with any acquisition or stimulation system of your choice.
- Suitable for rodent, large animal, and non-human primate.
- All cuffs feature biocompatible and chronically stable materials suitable for long term (multiple month to multiple year) implantation.
Metal Type
Characteristics
- Multiple inner diameter alternatives, from 5 mm to 56 µm.
- Strong leads with fully customizable location, angle and type of encapsulation.
- Complete flexibility on number of contacts and their arrangement.
- Available with a wide variety of connector types, as well as bare wires.
- All cuffs feature biocompatible and chronically stable materials suitable for long term (multiple month to multiple year) implantation.
- More than 2 years of chronic stimulation reported.
Details
| Standard (1.0 - 5.0 mm i.d.) | |
|---|---|
| Contact material & thickness | d=inner diameter (i.d.) |
| * Recommended for stimulation | |
| 125 µm stranded Stainless Steel | 1.0 - 5.0 mm |
| 100 µm Platinum | 1.0 - 2.0 mm |
| * 250 µm Platinum | 2.0 - 5.0 mm |
| Microcuffs (0.75, 0.5 and 0.3 mm i.d.) | |
|---|---|
| Contact material & thickness | d=inner diameter (i.d.) |
| 100 µm Platinum | 0.5 & 0.75 mm |
| 50 µm Platinum/Iridium | 0.3 mm |
| Nanocuffs (56 - 250 µm i.d.) | |
|---|---|
| Contact material & thickness | d=inner diameter (i.d.) |
| 25 µm Platinum/Iridium | 160 - 250 µm |
| 12.5 µm Platinum/Iridium | 56 - 140 µm |
Introduction
The concentric nerve cuff features rings of multiple independently-addressable contacts spaced evenly around the cuff, and allows for recording or stimulation at different locations around the nerve, to assist in targeting individual fascicles or avoiding vasculature.
The number of contacts allowed per ring is a function of the inner diameter of the cuff.
| Number of contacts per ring | |
|---|---|
| Cuff I.D. | Maximum # of contacts |
| 1.5 mm | 8 (50 µm wire) |
| 1.0 mm | 6 (50 µm wire) |
| 0.75 mm | 5 (50 µm wire) |
| 0.5 mm | 4 (50 µm wire) |
| 0.3 mm | 3 (25 µm wire only) |
Details
Multiple contacts at a single section of the nerve, allowing recording or stimulation at different locations circumferentially.
d Inner diameter, n Number of contacts, w Number of contacts inside a ring (2-8), x Spacing between contacts, y Distance from the end of the ring to the end of the cuff, s Teflon insulated stranded Stailess Steel lead| Standard (1.0 - 5.0 mm i.d.) | |
|---|---|
| Contact material & thickness | d=inner diameter (i.d.) |
| * Recommended for stimulation | |
| 125 µm stranded Stainless Steel | 1.0 - 5.0 mm |
| 100 µm Platinum | 1.0 - 2.0 mm |
| * 250 µm Platinum | 2.0 - 5.0 mm |
| Microcuffs (0.75, 0.5 and 0.3 mm i.d.) | |
|---|---|
| Contact material & thickness | d=inner diameter (i.d.) |
| 100 µm Platinum | 0.5 & 0.75 mm |
| 50 µm Platinum/Iridium | 0.3 mm |
| Nanocuffs (56 - 250 µm i.d.) | |
|---|---|
| Contact material & thickness | d=inner diameter (i.d.) |
| 25 µm Platinum/Iridium | 160 - 250 µm |
| 12.5 µm Platinum/Iridium | 56 - 140 µm |
Introduction
Our X-Wide Contact Nerve Cuffs feature large 500 µm-width platinum-iridium ribbon contacts with significantly larger surface area than typical contacts. These large contacts allow the X-Wide Contact cuffs to deliver greater stimulation currents at safer voltage levels, and typically provide much lower functional thresholds. This feature makes these cuffs suitable for high-intensity stimulation applications such as high frequency nerve blocking.
The reduced contact impedances are ideal for ensuring that the output of the stimulation source is not attenuated, and that potentially harmful effects such as charge buildup are more easily avoided.
| SUGGESTED NERVE CUFF DIAMETER (RAT) | ||
|---|---|---|
| Nerve | Nerve diameter (mm) | Cuff diameter (mm) |
| Sciatic | 1.9 | 2.50 |
| Tibial | 1.2 | 1.5 |
| Cervical Vagus | 0.5 | 0.75 |
| Sympathetic Chain | 1.43 | 2 |
| Subdiaphragmatic Vagus | 0.3 | 0.5 |
Details
The X-wide surface area cuffs are ideal for studies using kilohertz electrical stimulation to achieve block of activity in peripheral nerves.
d Inner diameter, n Number of contacts, x Spacing between contacts, W Width of contact, W = 0.5 mm (Platinum/Iridium 90/10), y Distance from the end of the contacts to the end of the cuff, s Teflon insulated stranded Stailess Steel leadLead Angles
90º Degrees
Parallel to the Cuff
45º Degrees
Connectors
Banana Terminal
Touch Proof
Pedestal Invivo1
Omnetics Connector
Encapsulation Options
Totally Encapsulated
Partial Encapsulated
